Refine your search
Collections
Co-Authors
Journals
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Pathak, A. K.
- Evaluation of Tissue Protective Activity of Tinospora cordifolia Stems in Irradiated Swiss Albino Mice with 60Co Radiation
Abstract Views :416 |
PDF Views:393
Authors
Source
Journal of Natural Remedies, Vol 10, No 1 (2010), Pagination: 32-35Abstract
In the present study, wholesome tissue protective efficiency of the ethanolic extract of Tinospora cordifolia stems in mice in terms of whole body survival, genotoxicity, cell proliferation and hematological profile have been investigated. The animals were divided into four groups having six animals in each. Group I, (Control), received vehicle, Group II received orally ethanolic extract of Tinospora cordifolia (500mg/kg), Group III was irradiated with 60Co radiation (external gamma radiation of 4 GY for 24h), and animals of Group IV were irradiated with 60Co radiation (external gamma radiation of 4 GY for 24 h) and given orally ethanolic extract of Tinospora cordifolia (500mg/kg), for seven days. On the 8th day all the animals were sacrificed, the blood was collected and hematological cell profile was analyzed. Intestine was removed and its histopathology was done and their mitotic index and crypt of villi was counted. The drug shows significant tissue protective activity (P<0.05) and shows normalization in hematological cell profile in irradiated animals.Keywords
Co RadiationFull Text
- Studies on Antigenotoxic Effect of Piper betle Leaves
Abstract Views :446 |
PDF Views:391
Authors
Source
Journal of Natural Remedies, Vol 7, No 2 (2007), Pagination: 247-251Abstract
Objective: To study the antigenotoxic effect of Piper betle leaves in Gamma irradiation and Cyclophosphamide treated animals. Materials and methods: Swiss albino mice were given 50% methanolic extract (100mg/kg body weight.) of Piper betle leaves and antigenotoxic effect was studied after whole body gamma irradiation (4Gy) & cyclophosphamide (50mg/kg body weight.) treatment. Bone marrow protection was studied by scoring aberration in metaphase chromosomes. Results: No drug toxicity was observed at given dose (100mg/kg body weight.) Methanol extract ½ hr prior to irradiation protects animals against Gamma irradiation & Cyclophosphamide treatment.Keywords
Anti-genotoxic Activity, Piper betle, Gamma Irradiation, CyclophosphamideFull Text
- Studies on Anti-genotoxic Effect of Piper betle Leaves
Abstract Views :490 |
PDF Views:425
Authors
Source
Journal of Natural Remedies, Vol 7, No 2 (2007), Pagination: 247-251Abstract
Objective: To study the antigenotoxic effect of Piper betle leaves in Gamma irradiation and Cyclophosphamide treated animals. Materials and methods: Swiss albino mice were given 50% methanolic extract (100mg/kg body weight.) of Piper betle leaves and antigenotoxic effect was studied after whole body gamma irradiation (4Gy) & cyclophosphamide (50mg/kg body weight.) treatment. Bone marrow protection was studied by scoring aberration in metaphase chromosomes. Results: No drug toxicity was observed at given dose (100mg/kg body weight.) Methanol extract ½ hr prior to irradiation protects animals against Gamma irradiation & Cyclophosphamide treatment.Keywords
Anti-genotoxic Activity, Piper betle, Gamma Irradiation, CyclophosphamideFull Text
- Evaluation of a Polyherbal Preparation for Wound Healing Activity
Abstract Views :200 |
PDF Views:0
Authors
Affiliations
1 Department of Pharmacognosy, Barkatullah University, Bhopal (M.P.), IN
2 Department of Pharmacognosy, VNS Institute of Pharmacy, Bhopal (M.P.), IN
1 Department of Pharmacognosy, Barkatullah University, Bhopal (M.P.), IN
2 Department of Pharmacognosy, VNS Institute of Pharmacy, Bhopal (M.P.), IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 2, No 5 (2010), Pagination: 340-342Abstract
The wound healing property of polyherbal formulation containing the extract of Psidium guajava and Ficus religiosa was evaluated in excision and burn wound model. The formulation responded significantly in both the wound models tested. The results were comparable in terms of wound contracting ability and epithelialization time. Thus, this exploration confirms the use of formulation containing the extract of Psidium guajava and Ficus religiosa as a wound healing agent.Keywords
Psidium guajava, Ficus religiosa, Polyherbal.
References
- Cohen K, Diegelmann R and Lindblad W. Wound Healing, Biochemical and clinical Aspects. 1992; W.B. Sounders, Philadelphia.
- Reddy G. Laser photo stimulation accelerates wound healing in diabetic rats. Wound Repair Regeneration 2001; 9: 248–255.
- Zakaria Muhammad bin and Mohd Mustafa Ali. Traditional Malay Medicinal Plants. 1994.
- Kirtikar KR and Basu BD. Indian Medicinal Plant. 1976; Vol. II, 2nd ed, M/s Bishwas Singh, Nirali prakasan, Dehradun, 1045-1048.
- Williamson Elizabeth M. Major herbs of Ayurveda. Churchill Livingstone. 2002.
- Anonymous. 1953; British Pharmacopoeia. General Medical Council, The Pharmaceutical Press, 17, Bloomsbury Square, London, W CI.P.
- Kamath JV, Rana AC and Chowdhury AR. Prohealing effect of Cinnamomum zeylanicum bark. Phytother. Res. 2003; 17: 970-972.
- Subramanian S, Sathish Kumar D and Arulselven P. Wound healing potential of Aloe vera leaf gel studied in experimental rabbits. Asian Journal of Biochemistry. 2006; 1 (2): 178-185.
- Mortan JP and Melone MH. Wound healing property and its pharmacodynamics of some terrestrial plants. Arch. Intern. Pharmacodyn and Therap. 1972; 196 (6): 117-121.
- Holla RK, Sequeria RP and Kulkarni DR. Cylosporin and wound healing. Indian J. Exp. Biol. 1998; 26: 869-873.
- Peacock EE Jr. Wound repair: Structure, synthesis and interaction of fibrous protein matrix. 1984; 3rd Ed. Peacock EE Jr. Philadelphia, W.B. Saunders Company, 56-101.
- Devipriya S and Shyamladevi CS. Protective effect of quercetin in cisplatin induced cell injury in the kidney. Indian J Pharmacol. 1999; 13: 422.
- Aljancic IS, Macura N, Juranic S, Andjelkovic N Randjelkovic and Milosavljevic S. Diterpenes from Achillea clyopetala. Phytochemistry. 1996; 43. 169-171.
- Evaluation of Anti-Diabetic Activity of Leaves and Fruits of Ficus religiosa
Abstract Views :147 |
PDF Views:0
Authors
Affiliations
1 Sagar Institute of Research, Technology and Science –Pharmacy (SIRTS-P), Bhopal, IN
2 Sagar Institute of Research and Technology-Pharmacy, Bhopal, IN
3 Sagar Institute of Research, Technology and Science – Pharmacy, Bhopal, IN
4 Department of Pharmacy, Barkatullah University, Bhopal-462 026 (M.P.), IN
1 Sagar Institute of Research, Technology and Science –Pharmacy (SIRTS-P), Bhopal, IN
2 Sagar Institute of Research and Technology-Pharmacy, Bhopal, IN
3 Sagar Institute of Research, Technology and Science – Pharmacy, Bhopal, IN
4 Department of Pharmacy, Barkatullah University, Bhopal-462 026 (M.P.), IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 1 (2010), Pagination: 61-63Abstract
The ethanolic extract of the leaves and fruits of Ficus religiosa Linn. was evaluated for its antidiabetic activity in normal rats and alloxan induced diabetic rats. Fruit extracts were found to have no effect on normal rats while they were effective in lowering the elevated blood glucose level in experimental diabetic rats. Fruit extract in a dose of 250 mg/kg body weight was found to be more effective than 100 mg/kg body weight.Keywords
Ficus religiosa, Antidiabetic, Alloxan Diabetic Model.- Evaluation of Wound Healing Activity of Ageratum conyzoides Linn
Abstract Views :159 |
PDF Views:0
Authors
Affiliations
1 Sagar Institute of Research Technology and Science –Pharmacy, Bhopal, IN
2 Sagar Institute of Research Technology and Science-Pharmacy, Bhopal, IN
3 Department of Pharmacy, Barkatullah University, Bhopal, IN
1 Sagar Institute of Research Technology and Science –Pharmacy, Bhopal, IN
2 Sagar Institute of Research Technology and Science-Pharmacy, Bhopal, IN
3 Department of Pharmacy, Barkatullah University, Bhopal, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 1, No 3 (2009), Pagination: 217-219Abstract
The present study was aimed to investigate the possible effect of Ageratum conyzoides leaf extract on wound healing activity on the excision would model. The wound healing property of Ageratum conyzoides appears to be due to the presence of its active principles, which accelerates the healing process and confers breaking strength to the healed wound.Keywords
Wound, Wound Healing, Ageratum, Ethanolic Extract, Excision Model.- Various Methods for Synthesis of Purine Analogues
Abstract Views :227 |
PDF Views:0
Authors
Affiliations
1 Department of Pharmaceutical Sciences, Saroj Institute of Technology and Management, Lucknow, IN
1 Department of Pharmaceutical Sciences, Saroj Institute of Technology and Management, Lucknow, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 9 (2011), Pagination: 1361-1365Abstract
The purine analogues are new class of nonclassical antimicrobial agents that binds with riboswitches. Purine (adenine) analogues are having antimicrobial, antifungal, antitumour, antiproliferative, antiviral and activity against HSV-1. Riboswitches are structured RNA domains that can bind directly to specific ligands and regulate gene expression. These RNA elements are located most commonly within the non-coding regions of bacterial mRNAs, because these genes were involved in fundamental metabolic pathways in certain bacterial pathogens. Purine-binding riboswitches may be targets for the development of novel antimicrobial agents. Designed compounds are bound by a purine riboswitches aptamer in vitro with affinities comparable to that of the natural ligand, and several also inhibit microbial growth.Keywords
Purines, Synthesis.- Chemistry of Fullerene and it’s Application:A Review
Abstract Views :197 |
PDF Views:0
Authors
Affiliations
1 Saroj Institute of Technology and Management, Lucknow, U.P., IN
2 Pranveer Singh Institute of Technology, Kanpur, U.P., IN
1 Saroj Institute of Technology and Management, Lucknow, U.P., IN
2 Pranveer Singh Institute of Technology, Kanpur, U.P., IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 2 (2010), Pagination: 234-242Abstract
The discovery of fullerenes has opened a new chapter on the physics and chemistry of carbon. So far, the physical and chemical properties of fullerenes are still under investigation. More research is needed to be done to confirm the suitability of some important application. Some potential applications will need more time for them to become reality. Their unique carbon cage structure coupled with immense scope for derivatization makes fullerenes a potential therapeutic agent. Henceforth chemistry and various potential therapeutic applications of fullerenes have been reviewed in the present paper. These include anti HIV-protease activity, photodynamic DNA cleavage, free radical scavenger, antimicrobial action and use of fullerenes as diagnostic agents.Keywords
Fullerenes, Anti-HIV Agent, Antibacterial Agent, DNA Photo Cleavage, Anti-Oxidant.- Theoretical Thermal Model of MIG Welding of FSS (AISI 430) Using ANSYS and its Experimental Verification
Abstract Views :318 |
PDF Views:8
Authors
Affiliations
1 Hatia, Ranchi, 834003, IN
2 NIFFT, Hatia, Ranchi, 834003, IN
1 Hatia, Ranchi, 834003, IN
2 NIFFT, Hatia, Ranchi, 834003, IN
Source
Indian Welding Journal, Vol 51, No 3 (2018), Pagination: 73-80Abstract
Metallurgical and mechanical properties of a weldment depend on its cooling rate and temperature distribution during welding. Temperature distribution and cooling rate are responsible for formation of different microstructures and different size of grain in different zones. If cooling rate and temperature distribution can be predicted in advance it will help the design engineer at the design stage itself to design a good welded joint. Determination of cooling rate and temperature distribution in welding experimentally is very costly and time taking. In this work the cooling rate and temperature distribution was theoretically predicted using ANSYS14 and experimentally verified. For the theoretical thermal analysis, 3D modeling of thermal simulation of arc welding (MIG) process was done by using ANSYS14. The special feature of the analysis is the use of a fast iterative procedure during a single pass welding. Temperature dependent metal properties of AISI 430 were taken from standard data source and were utilized till to the liquid phase. Element shape '3-D 10-Node tetrahedral' (solid 87) was used in 3-D analysis. Conduction and convection are considered as heat transfer mode. The experimental values of welding speed, welding current, and arc voltage were used for theoretical analysis. Thermocouples were used to record welding temperature using data tracker and computer. Five thermocouples were fixed at the middle line of the plate to measure temperature distribution and cooling rate practically. Two plates of FSS were welded by MIG welding in butt joint position in single pass.Keywords
Ferritic Stainless Steel, MIG Welding, Cooling Rate, Temperature Distribution, Thermocouple, ANSYS.References
- Lippold JC and Kotecki DJ (2005); Welding Metallurgy and Weldability of Stainless Steels, John Wiley and Sons, p.87.
- Tekriwal P and Mazumder J (1988); Finite element analysis of three-dimensional transient heat transfer in GMA welding, Welding Journal, Research and Development, pp.150s-156s.
- Negi V and Chattopadhyaya S (2013); Critical assessment of temperature distribution in submerged arc welding process, Advances in Materials Science and Engineering, Article ID 543594, pp.1-9.
- Kumar KS (2015); Investigation on transient thermal responses on 316L austenitic stainless steel and low carbon ferritic steel welding using pulsed Nd: YAG laser, Material Science & Engineering, 4(6), pp.1-9.
- Ho GY and Chu TK (1977); Electrical resistivity and thermal conductivity of nine selected AISI stainless steels, CINDAS Report 45, Prepared by American Iron and Steel Institute, p.37.
- ASM Handbook (1993); vol. 6, ASM International, p.71.
- http://www.engineeringtoolbox.com/convective-heattransferd_430.html
- ANSYS 14.5 Help Desk Element Type.
- Pathak AK and Datta GL (1999); Three-dimensional finite element analysis of heat flow in arc welding, Indian Welding Journal, 32(3), pp.32-38.
- Silva PN and Narayanan Sankar TK (1996); Finite element analysis of temperature distribution during arc welding using adaptive grid technique, Welding Journal, 75(4), pp. 123s-128s.
- Ismail MIS and Afieq WM (2016); Thermal analysis on a weld joint of aluminium alloy in gas metal arc welding, Advances in Production Engineering and Management, 11(1), pp.29-37.
- Three Dimensional Finite Element Analysis of Heat Flow in Arc Welding
Abstract Views :213 |
PDF Views:4
Authors
A. K. Pathak
1,
G. L. Datta
2
Affiliations
1 Prodn Engg and Mgt Dept, RIT Jamshedpur, 831014, IN
2 Mechanical Engineering Department, IIT Kharagpur, 721302, IN
1 Prodn Engg and Mgt Dept, RIT Jamshedpur, 831014, IN
2 Mechanical Engineering Department, IIT Kharagpur, 721302, IN
Source
Indian Welding Journal, Vol 32, No 3 (1999), Pagination: 32-38Abstract
in the present paper a three dimensional transient finite element analysis of heat flow in arc welding has been presented. The problem was solved by considering the important factors that influence the heat transfer in arc welding, like, temperature dependent material properties, enthalpy and stirring effect in the molten pool. To reduce the computation time, finer mesh was generated where temperature gradient was too high and gradually mesh size was increased away from the heat source. Variations of temperature along the cross section at two positions of the arc were plotted and compared with the experimental and calculated values available in the literature. Temperature history curve was also plotted and compared with the published results.- 3 -d Finite Element Analysis on Heat flow In Welding Under Varying ARC Lengths
Abstract Views :398 |
PDF Views:4
Authors
A. K. Pathak
1,
G. L. Datta
2
Affiliations
1 Prodn Engg & Mgt Dept., RIT, Jamshedpur - 831 014, IN
2 Mechanical Engineering Dept., IIT, Kharagpur - 721 302, IN
1 Prodn Engg & Mgt Dept., RIT, Jamshedpur - 831 014, IN
2 Mechanical Engineering Dept., IIT, Kharagpur - 721 302, IN
Source
Indian Welding Journal, Vol 33, No 4 (2000), Pagination: 24-29Abstract
Arc length is an important variable affecting the heat flow in welding. In the present paper, a three-dimensional transient finite element analysis on heat flow in arc welding under varying arc length conditions have been presented The problem was solved by considering the important factors that influence the heat transfer in arc welding, like temperature dependent material properties, enthalpy and stirring effect in molten pool. To reduce the computational time, the finer mesh was generated where the temperature gradient was too high and gradually mesh size was increased away from the heat source. Temperature distribution in the plate and variations of temperature along the cross-section at two positions of the arc for three arc radii were plotted for comparison.Keywords
Heat Flow, FE Analysis, Arc Welding, Arc Radius. 1.0.- Revisiting Some Pal Type Birkhoff Interpolation Problems
Abstract Views :253 |
PDF Views:0
Authors
Affiliations
1 Department of Higher Education, OSD, IN
2 Department of Mathematics, Sant Hirdaram Girls College, Bhopal, IN
1 Department of Higher Education, OSD, IN
2 Department of Mathematics, Sant Hirdaram Girls College, Bhopal, IN
Source
The Journal of the Indian Mathematical Society, Vol 86, No 1-2 (2019), Pagination: 118-125Abstract
In this paper we revisit Pal type Birkhoff interpolation for the sets consisting of zeros of polynomials with complex coefficients with two or more additional nodes at value nodes. We also evaluate regularity of (0, 2) Pal type Birkhoff interpolation on the zeros of the polynomials obtained by applying mobius transform to the zeros of ischolar_mains of unity with one additional complex node at value nodes.Keywords
Lacunary Interpolation, Non-uniformly Distributed Nodes, Pal Type Birkhoff Interpolation, Regularity, Roots of UnityReferences
- L. G. Pal, A new modification of the Hermite-Fejer interpolation, Anal. Math., 1 (1975), 197−205.
- O. Kis, Notes on interpolation, Acta. Math. Acad. Sci. Hungar., 11 (1960) 49−64. (In Russian)
- G. G. Lorentz, S. D. Riemschneider and K. Jetter, Birkhoff interpolation, Addison-Wesley, Mass., (1983).
- W. Chen and A. Sharma, Lacunary interpolation on some non-uniformly distributed nodes on the unit circle, Annales Univ. Sci., Budapest., (Sectio Computatorica) 16 (1996), 69−82.
- M. G. de Bruin and A. Sharma, Birkhoff interpolation on perturbed ischolar_mains of unity on the unit circle, J. Nat. Acad. Math. India, 11 (1997), 83−87.
- M. G. de Bruin, A. Sharma and J. Szabados, Birkhoff-type interpolation on perturbed ischolar_mains of unity, in: Approximation Theory in Memory of A. K. Varma, N. K. Govil, R. N. Mohapatra, Z. Nashed, A. Sharma and J. Szabados (Eds.), Marcel Dekker, New York, (1998), 167−179.
- M. A. Bokhari, H. P. Dikshit and A. Sharma, Birkhoff interpolation on some perturbed ischolar_mains of unity: revisited, Numer. Algorithms, 25 (2000) 47−62.
- H. P. Dikshit, Birkhoff interpolation on some perturbed ischolar_mains of unity, Nonlinear Analysis Forum, 6 (2001), 97−102.
- H. P. Dikshit, Pal-type interpolation on non-uniformly distributed nodes on the unit circle, Journal of Computational and Applied Mathematics, 155 (2003), 253−261.
- M. G. de Bruin and H. P. Dikshit, Pal-type Birkhoff interpolation on nonuniformly distributed points, Numerical Algorithm, 40 (2005), 1−16.
- M. G. de Bruin, (0,m) Pal-type interpolation on the mobius transform of ischolar_mains of Unity, Journal of Computational and Applied Mathematics, 178 (2005), 147−153.
- A. K. Pathak, A Birkhoff interpolation problem on unit circle in the complex plane, J. Indian Math. Soc., 73 (2006), 227−233.
- R. Brueck, Lagrange interpolation in non-uniformly distributed nodes on the unit circle, Analysis 16 (1996), 273−282.
- A. Mandloi and A. K. Pathak, (0,2) Pal-type interpolation on a circle in the complex plane involving mobius transform, Numer. Algorithms, 47 (2008), 181−190.
- Geeta Modi, Anil Kumar Pathak and Anita Mandloi, Some cases of Pal-type birkhoff interpolation on zeros of polynomials with complex coefficients, Rocky Mountain Journal, 42 (2012), 711−727.